Leukaemia
Lung
Breast
Ovary
Prostate
Stomach
Colon
Pancreas
Brain
Melanoma
Bladder
Liver
Cervical
Anal
Gallbladder
Oropharynx
Larynx
Nasopharynx
Hypopharynx
Oesophagus
Vulva
Oral
Testis
Uterine
Kidney
Tryroid
NonHodgkin
Hodgkin
Myeloma
5-Fluorouracil
116
125
38
13
55
251
224
120
111
65
73
97
88
172
58
68
1
3
127
4
0
0
0
Sorafenib
207
283
168
229
211
35
162
0
8
0
6
14
2
1
0
78
1
14
176
30
0
46
Docetaxel
1
25
104
1
33
55
1
6
9
0
27
19
31
32
20
0
29
2
20
2
11
0
0
0
Paclitaxel
54
85
82
184
142
13
16
1
14
8
15
9
22
10
5
34
304
5
16
0
0
1
Gemcitabine
178
234
26
16
73
47
25
15
7
7
124
0
0
3
0
1
0
1
2
0
16
0
12
1
0
Mitomycin-C
142
210
66
7
111
0
56
99
57
19
3
0
1
3
5
16
1
0
2
5
0
1
0
2
Doxorubicin
200
256
103
65
212
38
9
9
0
0
6
2
5
1
1
46
101
29
68
Etoposide
286
292
118
164
37
8
175
28
57
0
15
1
3
0
0
1
0
2
3
0
6
6
5
191
CGP-082996
118
160
57
88
30
82
64
121
27
32
16
0
3
1
1
2
1
1
1
21
1
9
10
7
34
2
17
Rapamycin
79
145
242
48
51
24
15
50
171
34
6
47
1
0
2
0
0
0
1
0
0
2
0
31
10
23
1
19
Erlotinib
2
109
26
3
2
77
41
7
1
5
0
3
2
1
0
1
1
1
1
6
0
1
18
1
0
0
0
Gefitinib
8
256
15
48
7
92
112
48
4
11
10
1
2
1
1
0
3
1
2
3
2
1
3
16
9
0
0
1
Vorinostat
58
37
50
8
23
13
18
100
85
3
1
8
4
1
1
1
0
0
0
1
0
3
0
0
1
2
41
1
30
Camptothecin
212
225
34
272
174
27
7
10
63
26
4
0
0
1
0
3
0
0
2
5
3
0
5
1
0
SN-38
5
90
94
2
249
100
1
2
5
24
19
8
0
0
0
1
3
0
0
3
2
1
0
2
1
0
Irinotecan
7
94
119
3
125
2
5
8
38
42
6
0
0
0
0
7
0
0
8
2
1
0
2
1
0
Tretinoin
64
185
3
22
1
0
7
30
248
3
5
9
0
0
0
0
0
0
0
2
10
2
0
5
95
7
0
10
GSK269962A
20
71
239
6
0
3
2
68
0
47
2
0
1
0
0
0
0
1
1
0
1
2
8
0
0
0
0
GSK429286A
57
221
7
0
1
1
65
0
44
2
0
1
0
0
0
0
0
0
0
1
1
7
0
0
0
0
Olaparib
9
35
75
9
9
19
4
3
2
1
7
3
2
2
1
1
1
1
0
1
1
16
1
1
2
0
0
Vinorelbine
14
55
136
0
10
2
3
4
19
0
11
2
0
1
1
1
2
3
1
0
3
0
2
0
15
45
6
Topotecan
54
200
112
26
0
9
2
24
2
0
0
38
1
0
0
0
0
0
0
0
1
0
3
0
0
0
0
1
Tamoxifen
0
45
128
62
0
8
3
9
51
0
12
1
6
0
0
0
0
0
0
13
0
0
1
18
-0
0
0
Vinblastine
67
68
0
12
0
23
125
0
7
2
0
0
0
2
1
1
3
0
0
179
1
14
Methotrexate
16
0
57
27
0
25
22
0
0
0
0
0
1
2
1
0
2
5
14
0
0
0
8
Bleomycin
130
9
36
1
0
5
0
13
150
67
0
121
14
0
1
21
14
6
7
49
28
0
2
11
2
Dabrafenib
3
46
1
1
0
1
19
2
8
0
1
0
2
1
1
1
1
1
1
1
1
1
1
2
35
0
0
1
PLX-4720
3
3
1
1
1
0
12
1
13
230
1
1
1
1
2
2
1
2
2
2
1
1
1
1
2
39
1
0
1
PLX4720
3
3
1
1
1
0
12
1
13
230
1
1
1
1
2
2
1
2
2
2
1
1
1
1
2
39
1
0
1
Trametinib
13
69
9
6
1
2
30
36
17
1
2
0
1
1
1
1
1
1
1
1
0
1
3
2
20
0
0
2
AZD6244
10
81
15
11
1
5
39
12
7
115
1
5
0
0
1
1
1
3
1
1
1
0
1
2
2
37
1
0
4
Selumetinib
10
81
15
11
1
5
39
12
7
115
1
5
0
0
1
1
1
3
1
1
1
0
1
2
2
37
1
0
4
Temozolomide
7
26
2
0
0
0
3
1
0
0
0
1
0
0
0
0
0
1
0
0
0
0
0
0
1
0
0
Rucaparib
1
3
28
142
9
1
2
6
1
1
1
1
2
1
1
1
1
2
2
3
1
1
1
2
1
1
0
0
0
NVP-TAE684
0
5
8
2
2
3
0
1
101
0
6
9
6
0
1
1
1
1
1
0
0
0
1
0
28
1
13
3
4
TAE684
0
5
8
2
2
3
0
1
101
0
6
9
6
0
1
1
1
1
1
0
0
0
1
0
28
1
13
3
4
Cyclopamine
2
4
4
7
14
10
3
56
38
1
1
2
0
1
2
1
0
1
1
1
0
0
0
0
0
1
0
0
1
Thapsigargin
19
0
0
0
29
0
0
1
54
1
0
0
0
0
0
0
0
0
0
1
0
8
0
0
0
1
0
0
1
NG-25
2
0
1
0
0
0
1
0
56
23
0
0
0
1
1
1
0
1
1
3
0
0
0
0
1
0
0
0
0
ZSTK474
0
0
19
0
0
13
36
21
0
6
0
3
0
3
9
1
0
1
1
1
0
0
0
0
0
12
0
0
0
CAY10603
6
3
4
6
1
1
3
1
4
2
0
1
2
1
2
2
1
2
2
2
1
1
1
1
1
0
3
3
24
PHA-665752
1
21
4
5
2
19
4
3
1
1
2
2
1
2
2
2
1
2
2
2
1
1
1
1
3
6
1
0
1
PD-0325901
11
16
2
3
2
1
7
8
2
24
1
0
0
1
2
1
1
3
1
1
1
2
1
1
1
6
0
0
0
PD0325901
11
16
2
3
2
1
7
8
2
24
1
0
0
1
2
1
1
3
1
1
1
2
1
1
1
6
0
0
0
Enzastaurin
0
5
1
2
0
3
21
6
3
3
0
4
0
15
3
2
1
1
2
0
0
0
0
0
1
1
3
0
3
XAV939
2
14
2
5
3
10
22
3
5
1
1
5
5
1
1
2
1
2
2
1
1
1
1
7
0
2
1
0
0
Embelin
25
16
19
0
1
0
3
2
0
12
6
2
0
0
0
0
0
0
0
0
0
0
0
3
0
0
-0
0
0
Seliciclib
20
5
23
2
5
0
8
2
2
5
4
1
2
2
2
2
0
2
1
1
0
1
0
0
3
0
0
0
7
Pictilisib
9
7
44
7
2
1
3
9
5
8
2
1
2
2
1
1
1
2
2
1
1
1
1
4
1
5
4
1
2
AZD0530
3
35
37
13
12
5
4
5
1
2
2
1
1
1
2
2
1
2
2
2
1
1
1
1
6
4
0
0
2
Saracatinib
3
35
37
13
12
5
4
5
1
2
2
1
1
1
2
2
1
2
2
2
1
1
1
1
6
4
0
0
2
Luminespib
15
34
26
2
8
5
8
4
0
4
4
1
1
1
2
2
1
2
2
2
1
1
1
2
1
4
3
1
6
Motesanib
1
25
3
2
2
1
2
1
1
2
1
1
2
1
2
2
1
2
2
2
1
1
2
1
2
44
1
1
2
TKI258
11
12
16
0
8
5
5
8
1
3
8
2
1
1
2
2
1
2
2
2
1
1
1
15
49
2
1
0
10
KU-55933
3
16
45
3
21
1
11
0
6
14
13
3
5
2
1
1
1
1
1
1
6
3
1
5
42
15
26
10
6
Tivozanib
1
1
5
2
1
1
7
2
2
1
1
1
1
1
2
2
2
2
2
2
1
1
2
1
145
2
0
1
1
Temsirolimus
12
38
46
11
20
0
7
19
26
15
7
2
1
0
1
1
0
1
1
1
0
0
2
23
3
65
21
10
Axitinib
1
51
7
0
7
2
6
16
2
15
1
4
0
1
1
1
1
1
1
1
1
1
1
0
55
0
0
0
Pazopanib
0
76
15
53
4
1
3
0
0
8
7
1
9
0
1
1
1
1
1
1
0
0
1
5
44
0
0
2
PF2341066
2
15
11
2
9
5
4
3
9
0
7
1
2
1
1
0
1
1
2
1
2
0
1
7
8
35
2
1
Crizotinib
2
15
11
2
9
5
4
3
9
0
7
1
2
1
1
0
1
1
2
1
2
0
1
7
8
35
2
1
Alectinib
8
3
0
0
0
0
0
1
0
0
0
0
2
1
1
1
1
1
1
1
1
1
0
2
5
2
1
1
Afatinib
0
53
2
0
5
2
5
1
11
2
2
6
3
3
2
0
2
1
1
0
2
0
0
0
0
0
0
0
ZD-6474
1
124
16
4
5
0
3
1
8
0
0
1
0
1
0
0
1
1
1
0
0
1
0
0
3
279
0
0
1
Zibotentan
0
2
3
18
86
2
3
1
1
1
2
1
1
1
2
2
2
2
3
2
2
2
2
1
1
1
1
1
1
Bicalutamide
1
14
85
3
1
13
4
0
8
8
3
1
5
1
1
0
1
1
0
1
0
2
1
3
1
1
1
0
17-AAG
57
38
82
14
49
3
17
9
10
29
5
4
1
1
2
1
1
1
1
2
0
0
2
0
2
11
2
0
50
Tanespimycin
57
38
82
14
49
3
17
9
10
29
5
4
1
1
2
1
1
1
1
2
0
0
2
0
2
11
2
0
50
Dactolisib
23
30
48
13
16
9
32
16
17
13
6
1
2
3
1
1
1
3
4
1
1
1
1
8
11
2
11
3
7
MG-132
67
24
49
6
28
10
22
13
22
10
1
2
3
0
1
0
0
1
2
0
0
1
1
2
1
4
3
0
24
Doramapimod
5
18
127
21
22
4
34
23
8
9
1
2
1
0
2
1
1
1
1
1
1
2
2
4
2
0
1
0
3
AZD6482
5
9
123
9
19
0
30
0
4
1
2
0
7
5
1
1
2
1
2
6
2
2
5
4
1
0
1
2
2
PD-0332991
11
20
10
1
2
3
3
11
16
2
2
3
2
1
1
1
1
2
1
2
1
2
6
1
2
5
1
4
Palbociclib
11
20
10
1
2
3
3
11
16
2
2
3
2
1
1
1
1
2
1
2
1
2
6
1
2
5
1
4
EpothiloneB
0
27
75
52
22
0
4
4
3
2
2
0
1
0
1
1
1
1
2
1
1
1
1
2
6
0
0
1
1
Talazoparib
8
13
62
34
6
1
1
2
1
0
1
1
3
1
2
2
2
2
2
2
1
1
2
4
1
1
1
1
1
Quizartinib
61
0
2
0
0
0
0
0
0
0
1
0
0
1
2
0
1
1
1
1
1
0
0
0
0
0
0
0
Lapatinib
2
77
12
3
63
19
16
5
14
14
0
2
2
2
1
1
2
1
2
1
1
0
7
7
2
0
0
0
Sunitinib
17
269
82
12
24
12
32
17
13
53
11
11
0
2
1
1
0
1
1
1
0
1
3
2
156
0
0
1
Cabozantinib
1
76
7
5
90
3
3
6
4
2
7
10
0
0
1
1
1
3
1
1
1
1
2
0
266
0
0
1
MK-2206
0
6
9
3
1
1
1
2
1
1
0
0
0
0
1
1
1
0
1
0
55
2
1
0
0
0
Nutlin-3
75
14
20
11
5
0
10
3
3
18
0
4
0
2
1
1
1
1
1
1
1
0
3
0
3
0
11
1
9
Tozasertib
55
3
6
9
2
1
1
1
2
1
1
1
2
1
2
2
3
2
2
2
1
2
1
2
2
5
1
1
7
Parthenolide
57
10
23
1
10
2
9
11
2
6
2
3
2
0
1
1
1
1
1
1
1
2
1
0
1
0
1
0
5
JQ1
54
13
15
11
18
3
4
9
7
3
2
4
1
0
1
1
1
1
2
1
1
2
1
3
3
5
16
4
18
FMK
201
4
3
2
5
6
0
14
23
3
0
2
0
0
0
0
0
1
0
0
0
3
0
0
0
0
0
0
4
ObatoclaxMesylate
110
15
10
3
1
0
3
5
3
7
2
2
1
1
2
2
1
4
2
2
1
4
1
1
1
4
14
3
8
Bryostatin1
157
8
6
2
2
1
1
4
4
16
0
0
1
1
1
1
1
3
1
1
1
1
1
0
4
0
18
5
2
CMK
84
0
0
1
0
0
0
2
2
0
0
1
2
2
1
1
2
1
1
1
1
1
1
0
1
0
1
0
1
Navitoclax
84
7
1
2
0
0
0
3
2
1
0
1
0
0
1
1
0
1
1
1
0
1
0
0
0
0
8
3
3
Ruxolitinib
314
1
1
5
0
0
0
12
1
1
0
1
0
1
1
1
1
1
1
1
1
0
1
0
0
0
5
3
2
Nilotinib
0
0
0
0
0
0
0
0
6
0
1
0
1
1
1
0
1
1
1
0
0
0
0
1
0
0
0
3
GW843682X
0
0
0
1
0
0
0
4
1
0
0
0
0
1
0
0
1
1
0
0
0
0
0
0
0
0
0
0
GNF-2
219
1
0
0
0
0
0
0
0
0
0
1
0
2
1
1
1
2
2
1
1
1
1
1
0
0
0
0
0
SNX-2112
125
0
0
0
0
0
0
0
0
1
0
0
0
0
1
1
0
1
1
1
0
0
0
0
0
0
0
0
0
Midostaurin
8
2
1
0
1
1
1
5
4
1
0
0
1
1
1
1
1
2
1
1
1
1
1
2
0
1
0
4
Lestaurtinib
112
2
2
2
14
1
1
3
1
0
0
1
2
1
2
2
1
2
2
2
1
1
1
1
2
3
3
2
2
Bosutinib
6
11
0
2
0
1
3
0
0
0
2
1
4
1
1
1
1
2
1
1
2
1
1
0
7
1
0
4
Ponatinib
21
2
1
0
1
1
1
2
1
2
1
0
1
1
1
1
1
2
1
1
1
1
5
1
8
0
0
2
Dasatinib
47
36
6
29
1
3
15
21
13
0
3
0
49
0
1
1
1
1
0
0
3
0
1
6
5
5
1
7
Imatinib
15
2
1
1
0
16
1
2
46
0
0
46
34
0
3
0
1
0
0
0
1
0
0
26
1
1
0
9
Veliparib
176
28
11
34
0
5
4
5
0
14
0
1
2
0
0
0
2
1
0
1
0
0
0
0
12
0
77
33
4
Idelalisib
0
0
0
1
0
1
1
1
1
0
0
1
1
1
1
1
1
1
1
1
1
1
0
0
0
147
74
9
Belinostat
12
9
3
10
9
2
6
8
1
2
1
3
0
3
1
2
1
2
2
2
1
1
1
1
3
7
48
11
10
Bexarotene
14
38
21
1
0
0
1
0
0
3
1
2
0
0
1
1
1
1
2
1
1
1
1
0
2
22
8
0
Cytarabine
15
4
7
0
2
0
2
24
11
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
64
Lenalidomide
0
0
0
6
0
0
2
0
1
0
0
0
0
0
0
0
1
1
0
0
1
1
0
2
1
136
Bortezomib
46
22
14
23
0
5
30
9
21
0
1
1
1
1
0
0
0
1
0
0
2
0
0
6
3
126
Panobinostat
87
13
17
7
12
0
4
9
16
6
2
4
2
1
2
1
1
1
1
2
1
1
1
4
4
7
48
27
Compound:
Cancer:
P-value: